Razi Berry

Human milk oligosaccharides (HMOs) found in breastmilk may influence a child’s growth from infancy through early childhood, according to a study supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health (NIH). The study also suggested that maternal obesity may affect HMO composition in breastmilk. The study was led by Lars Bode, Ph.D., at the University of California, San Diego. It appears in The American Journal of Clinical Nutrition.

Human milk oligosaccharides (HMOs) serve as prebiotics and may influence a child’s growth from infancy through early childhood

HMOs are complex sugars found in breastmilk, but infants do not digest them directly. Instead, HMOs serve as prebiotics by influencing the composition of the gut microbiome. Previous studies have found that HMOs may also protect infants from disease-causing microbes. Approximately 150 types of HMOs are known, and mothers have unique combinations and concentrations of them in their breastmilk, influenced in part by genetics and the types of HMO-processing enzymes they have.

Approximately 800 pairs of mothers and children were evaluated in a Finnish study

Researchers evaluated approximately 800 pairs of mothers and children in a Finnish study of child development. The researchers analyzed the content of HMOs in breastmilk samples (collected when the children were 3 months old), among them two HMOs that are now added to some commercial infant formulas: 2′-fucosyllactose (2’FL) and lacto-N-neo-tetraose (LNnT).

Breastmilk from mothers of taller and heavier infants and overweight and obese mothers

Breastmilk from mothers of taller and heavier infants and children tended to have less diverse HMO composition, higher concentrations of 2’FL and lower concentrations of LNnT. Breastmilk from overweight and obese mothers also tended to have less diverse HMO composition, higher concentrations of 2’FL and lower concentrations of LNnT.

According to the authors, these results confirm findings of two of their previous smaller studies. Together, the three studies found similar patterns of HMO composition and child growth among three different groups of mothers. The authors noted that, although their study linked HMO composition with early childhood growth, it couldn’t prove that variations in HMO patterns cause differences in children’s growth. If additional studies confirm their findings, specific HMOs might one day provide a treatment for early childhood growth problems and obesity.

Source:

  1. Lagström, H., et al. (2020) Associations between human milk oligosaccharides and growth in infancy and early childhood. The American Journal of Clinical Nutrition. doi.org/10.1093/ajcn/nqaa010.

Razi Berry is the founder and publisher of the journal Naturopathic Doctor News & Review, which has been in print since 2005, and the premier consumer-faced website of naturopathic medicine, NaturalPath. She is the host of The Love is Medicine Project docuseries, The Natural Cancer Prevention Summit, The Heart Revolution-Heal, Empower and Follow Your Heart, and the popular 10-week Sugar Free Summer program. From a near death experience as a young girl that healed her failing heart, to later overcoming infertility and chronic fatigue syndrome and fibromyalgia through naturopathic medicine, Razi has lived the mind/body healing paradigm. Her projects uniquely capture the tradition and philosophy of naturopathy: The healing power of nature, the vital life force in every living thing and the undeniable role that science and mind/body medicine have in creating health and overcoming dis-ease. You can follow Razi on social media: Facebook at Razi Berry, Instagram at Razi.Berry and join the Love is Medicine group to explore the convergence of love and health. Look for more, and listen to more Love is Medicine podcast episodes here.

Recommended Posts

Leave a Comment