A new study from the University of California, Irvine, reveals a strong link between disruptions in the circadian rhythm—our body’s internal clock—and colorectal cancer (CRC) progression. The research shows how sleep patterns and biological timekeeping disturbances, such as those experienced by shift workers or frequent flyers, can influence gut health, leading to CRC risks. Specifically, the study found that circadian disruptions negatively affect the gut microbiome, allowing harmful bacteria to thrive and weakening the protective mucus barrier in the intestines. This increases inflammation and accelerates cancer development. These findings could pave the way for more personalized screening and prevention strategies for CRC, particularly for younger adults, where cases are rising. The study emphasizes the importance of maintaining healthy sleep cycles to mitigate CRC risk in the long term.
See also: Study Advocates for Colorectal Cancer Screening 5 Years Earlier
