Dog Dementia: Therapies & New Cure Might Help Humans Too

Dr. Carol Osborne, DVM

Does your dog get lost in your house?  Does your dog stare at the wall? Did your dog greet you at the door today?  Does your canine make mistakes indoors? Dog Dementia also referred to as Canine Cognitive Dysfunction Syndrome (CDS), affects approximately 12 percent of dogs age ten and older. What’s remarkable is that this disease pathology and signs in dogs mimics Alzheimer’s disease in humans.

What are the hallmark signs of dog dementia?

Progressive memory loss, disorientation, agitation, and confusion are the hallmark signs we usually associate with senility in pets and people. Unfortunately, this disease in dogs often leads to euthanasia as canines suffering from dementia also often end up making mistakes inside the home, an issue most pet owners find unacceptable.

What traditional treatment is available for dog dementia?

Current dog dementia therapies  include the drug Selegiline hydrochloride, which is also referred to as L-deprenyl.

L-deprenyl is available over the counter in many health food stores.

Selegiline hydrochloride acts by increasing the levels of an essential brain neurotransmitter called Dopamine. This medication is also sometimes used to treat Alzheimers and Parkinson’s Disease in people. It is sold under the name Anipryl for dogs. Aniprylhas been shown to temporarily reverse some of the signs of Canine Cognitive Dysfunction Syndrome (CDS) in dogs and improve behavior in about 75% of affected canines after 30-60 days.

What Natural Therapies Benefit Dog Dementia?

Natural therapies which have been reported to be beneficial in these dementia dogs include adding various antioxidants including the B-Vitamin Choline. Essential omega-3 fatty acid supplementation is also helpful for CDS.

What are some simple steps pet owners can take to improve the daily quality of life in their senior dog with or without canine dementia?

  • Create clever interactive games to stimulate your dog’s brain and extend his or her attention span
  • Exercise and play with your dog regularly. Go for short walks together, talk to them, pet them and love them several times a day.
  • Be sure your dog is safe even if you are at home during the day. Keep your dog on a leash when outside and offer a safe fenced in area so he or she can enjoy the outdoors and not wander off and get lost.
  • Keep your daily routine as strict as possible. This helps to minimize stress.
  • Offer an elevated platform for food and water bowls so eating and drinking are easy and dogs aren’t forced to reach and stretch their necks uncomfortably.
  • Keep a close eye on your dog even if he or she is outside in an enclosed area. Tell your dog verbally to eliminate so your dog knows why he or she is outside in case they forgot, and verbally praise good behavior.
  • Provide access to fresh clean water, preferably distilled at all times. Feed a high quality preferably organic diet or a homemade diet divided up into 2-3 small meals a day.

Are there any new therapies or potential cures for dog dementia?

Clinical trials for a possible cure for dog dementia are ongoing in Australia at the University of Sydney’s Brain and Mind Research Institute. Scientists here are working on a new therapy to cure CDS which they hope will lead to a similar cure for humans.

This therapy involves using stem cells created from the skin of a dog’s belly and transplanting them into the dog’s brain. Researchers hope that these new cells will survive in the brain, grow into brain cells and actually form connections with the dogs own brain. This would ultimately result in new brain cells, capable of memory retention which would function normally and improve overall memory in dogs suffering from dementia.

After 5 years, of trial and error, researchers have finally achieved success with memory restoration in demented rats. Their next step is dogs.

Australian scientists already have a group of dogs suffering from dementia who have been volunteered by their owners. Clinical trials are underway.

Dr. Valenzuela, who leads the team says, “They expect to see major memory improvements in this group of demented canines within the first three months!

Because Canine Cognitive Syndrome mimics Human Alzheimer’s Disease quite closely with respect to signs and brain pathology, scientists hope to begin clinical trials for people affected with Alzheimer’s disease within the next 3-5 years.

Although this therapy has yet to be proven as a cure for dog dementia, scientists feel extremely confident about its future potential for pets and people suffering from dementia.


Dr. Carol Osborne, DVM has gained national recognition as an authority in traditional and alternative veterinary medicine and health care for pets. She is our nation’s first veterinarian to be Certified as a Diplomat of the American Board of Anti-Aging Medicine. This status is for human medicine. Dr. Carol used that knowledge to create her pet longevity formulas. The founder and director of the Chagrin Falls Veterinary Center and creator of PAAWS, Pet Anti-Aging Wellness Systems, for dogs and cats. Dr. Carol has pioneered the exploration of new therapies for the treatment and prevention of age-related degenerative disease, as well as promotion of optimum health and performance for pets.

Dr. Carol’s first two books “Naturally Healthy Cats” and “Naturally Healthy Dogs” hit the international best seller lists. The multi-faceted Dr. Osborne is also an Emmy-nominated television journalist. “Dr. Carol” as she has come to be known, has gained national prominence through her frequent appearances on popular shows including Today in New York, where she was the on-camera staff veterinarian.

Dr. Carol is very familiar to audiences across the country through her numerous appearances on metropolitan news programs, in particular, the highly rated, nationally syndicated Fox morning news show, Good Day L.A. Many viewers enjoyed Dr. Carol’s weekly role as the pet product consumer reporter and staff veterinarian on the Fox News Channel’s Pet News and the Family Channel’s Home & Family where she was a recurring Featured guest for several years. Her numerous appearances on Discovery’s Animal Planet, including Pet Line, Amazing Tails and Disney’s Petsburg USA have made her a welcome face to audiences around the world. Dr. Carol was credited as a consultant on ABC’s Genesis Award Winner Incredible Animal Tales.

Dr. Carol has been featured in USA Today, USA Weekend, The Los Angeles Times and the New York Daily News. She has contributed columns to “Trends”, the highly respected journal of the American Animal Hospital Association, DVM Magazine, Dog Fancy, Natural Dog, Dog World, Veterinary Economics Magazine, The Washington Enquirer, Cat Fancy, Puppies USA, Groomer to Groomer, Icelandic Horse and Travel, and Equine Athlete. Her editorial contributions also include In Style Magazine, Woman’s World and Icon Magazine, as well as Fit Magazine and The National Enquirer.

Dr. Carol’s first two books have been translated into 12 different languages and sold over 200,000 copies. They are in their fourth publication by Marshall Editions. Dr. Carol also wrote the chapter, “Pets our Pets Don’t Need” in the book,”Infection Protection” published November, 2002 by Harper Collins. Currently Dr. Carol is the online veterinary expert for the highly acclaimed online resource Answers.com, the pet product consumer safety advisor for Dog Time Media. She is a veterinary news network reporter, and the featured online pet expert curator for Organized Wisdom dot com.

Dr. Carol hosts a weekly National Pet Talk AM Radio Show broadcast online and throughout the country on National AM Talk Radio. Dr. Carol is an accomplished equestrian and competed successfully on the “A” horse show circuit as an amateur and professionally. She qualified for the US Equestrian Olympic Team Trials. She is an avid horse lover and a respected member of the American Horse Show Association.

Dr. Carol earned her B.S. degree from John Carroll University; she graduated summa cum laude. She received her D.V.M. degree with honors from Ohio State University College of Veterinary Medicine and has been in private clinical practice for over 20 years. Currently, she practices at the Chagrin Falls Veterinary Center, in Chagrin Falls, Ohio and continues her research in developing advanced biosciences and natural regenerative therapies for the benefit of dogs and cats.

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