Razi Berry

New research from RCSI University of Medicine and Health Sciences demonstrates the beneficial effect of breast milk consumption on cardiovascular health and early cardiovascular development in premature infants.

Published in JAMA Network Open, the study of 80 preterm infants is the first of its kind to show that preterm infants with higher exposure their mother’s own milk had enhanced cardiac function at age one year, with values approaching those of healthy full-term infants.

The research was led by Professor Afif EL-Khuffash, Clinical Professor of Paediatrics at RCSI and Consultant Neonatologist at the Rotunda Hospital, Dublin, in collaboration with researchers at University of Oxford; Mount Sinai Hospital, Toronto; Northwestern University Feinberg School of Medicine; Washington University School of Medicine; and, Harvard Medical School.

Children and adults who are born preterm are at increased risk of cardiovascular disorders, including ischemic heart disease, heart failure, systemic and pulmonary hypertension, and are more likely to die as a result of cardiovascular disease. The hearts of young people born early are known to have unique traits such as reduced biventricular volume, shorter length, lower systolic and diastolic function and a disproportionate increase in muscle mass. This results in impaired heart function, which is significantly lower than that of healthy infants who are born at term. This dysfunction is detectable at hospital discharge and persists throughout their adolescence.

This study shows that exclusive breast milk consumption in the first months after birth is associated with a normalisation of some of these traits. Premature infants exposed to a high proportion of their mother’s own milk during the first few week after delivery had greater left and right heart function and structure with lower lung pressures and enhanced right heart response to stress at one year of age compared to preterm infants who had a higher intake of formula, with all measures approaching those seen in term-born healthy children.

These findings were apparent before discharge from the hospital and persisted up to a year of age (the duration of follow up).

Professor EL-Khuffash said: “This study provides the first evidence of an association between early postnatal nutrition in preterm-born infants and heart function over the first year of age, and adds to the already known benefits of breast milk for infants born prematurely.”

“Preterm infants have abnormal heart function. However, those who are fed their mother’s own milk demonstrate recovery of their heart function to levels comparable to healthy term born infants. Preterm infants fed formula do not demonstrate this recovery.”

1. Afif El-Khuffash, Adam J. Lewandowski, Amish Jain, Aaron Hamvas, Gautam K. Singh, Philip T. Levy. Cardiac Performance in the First Year of Age Among Preterm Infants Fed Maternal Breast Milk. JAMA Network Open, 2021; 4 (8): e2121206 DOI: 10.1001/jamanetworkopen.2021.21206

Razi Berry is the founder and publisher of the journal Naturopathic Doctor News & Review, which has been in print since 2005, and the premier consumer-faced website of naturopathic medicine, NaturalPath. She is the host of The Love is Medicine Project docuseries, The Natural Cancer Prevention Summit, The Heart Revolution-Heal, Empower and Follow Your Heart, and the popular 10-week Sugar Free Summer program. From a near death experience as a young girl that healed her failing heart, to later overcoming infertility and chronic fatigue syndrome and fibromyalgia through naturopathic medicine, Razi has lived the mind/body healing paradigm. Her projects uniquely capture the tradition and philosophy of naturopathy: The healing power of nature, the vital life force in every living thing and the undeniable role that science and mind/body medicine have in creating health and overcoming dis-ease. You can follow Razi on social media: Facebook at Razi Berry, Instagram at Razi.Berry and join the Love is Medicine group to explore the convergence of love and health. Look for more, and listen to more Love is Medicine podcast episodes here.

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