Razi Berry

When parents suffer from depression, kids may be at risk for physical health problems in young adulthood, according to a study from researchers including the University of Georgia’s Katherine Ehrlich.

Association between parental depression and youth metabolic syndrome

The results revealed an association between parental depression and youth metabolic syndrome; a condition that forecasts substantially increased risk for cardiovascular disease and diabetes.

The good news is that while parental depression was associated with metabolic syndrome in young adulthood, we found that there were characteristics that served as protective factors. The link was diminished for young adults who reported high levels of self-regulation and healthy lifestyles, important factors that shape physical health,” said Katherine Ehrlich, lead author and assistant professor of psychology in the Franklin College of Arts and Sciences, University of Georgia.

What previous research has shown

Previous research has shown that exposure to an accumulation of adverse childhood experiences; like poverty, maltreatment and mental illness in the family; can have a lasting influence on adult physical health, particularly chronic diseases associated with aging, including diabetes, heart disease, arthritis and some cancers.

This study focused on the following

This study focused on whether chronic exposure to parental depression across adolescence was predictive of youths’ later metabolic syndrome, a cluster of interrelated metabolic abnormalities that includes high blood pressure and blood sugar.

The sample for this study was taken from a larger sample of African American youths and their primary caregivers led by principal investigator Gene Brody, director of UGA’s Center for Family Research.

The subjects participated in 11 waves of data collection across childhood (ages 11-18) and into young adulthood. At age 25, 391 participants agreed to take part in a blood draw to assess young adult metabolic syndrome.

What encompasses a diagnosis of metabolic syndrome?

A diagnosis of metabolic syndrome involves high waist circumference (with ethnic and sex-specific cutoffs) plus two of the following four components: high blood pressure, raised triglyceride levels, raised fasting glucose levels and low levels of high-density lipoproteins (“good” cholesterol). The team’s analyses revealed that parental depression in adolescence was associated with a composite score reflecting components of metabolic syndrome in early adulthood.

These two factors were also found

They also found two factors that moderated this association: self-regulation; the ability to regulate and control attention, emotions and behavior; and a lack of unhealthy behaviors involving factors like diet, exercise, sleep and substance use.

But for youths with low self-regulation and two or more unhealthy behaviors; e.g., unhealthy diet and poor sleep; more exposure to parental depression was associated with components of metabolic syndrome at age 25.

“It’s not just parental depression; it’s parental depression in the context of low self-regulation and unhealthy behaviors,” Ehrlich said. “All three variables are important.”

“This study is a strong reminder that coping with chronic stress, for some young people, may affect the functioning of physiological systems in a way that increases their likelihood of developing metabolic syndrome, a precursor to many chronic diseases that appear during adulthood,” said Brody, emeritus professor in the College of Family and Consumer Sciences.

Team’s findings suggest the following

Ehrlich noted that while the team’s findings suggest that parental depressive symptoms were associated with a higher composite score for metabolic syndrome, there’s still hope for individuals who are just starting to show these warning signs of poor health. Factors that make up the metabolic syndrome composite are modifiable and can change in response to changes in diet, exercise, sleep and other aspects of self-care.

“For young adults exposed to a depressed parent in adolescence, efforts to promote self-regulation and healthy behaviors may be particularly important in establishing physical health as they move toward their 30s,” she said.


  1. Ehrlich, K.B., et al. (2019) Exposure to Parental Depression in Adolescence and Risk for Metabolic Syndrome in Adulthood. Child Development. doi.org/10.1111/cdev.13003.

Razi Berry is the founder and publisher of the journal Naturopathic Doctor News & Review, which has been in print since 2005, and the premier consumer-faced website of naturopathic medicine, NaturalPath. She is the host of The Natural Cancer Prevention Summit and The Heart Revolution-Heal, Empower and Follow Your Heart, and the popular 10 week Sugar Free Summer program. From a near death experience as a young girl that healed her failing heart, to later overcoming infertility and Chronic Fatigue Syndrome and Fibromyalgia through naturopathic medicine, Razi has lived the mind/body healing paradigm. Her projects uniquely capture the tradition and philosophy of naturopathy: The healing power of nature, the vital life force in every living thing and the undeniable role that science and mind/body medicine have in creating health and overcoming dis-ease. Follow Razi on social media: Find her on Facebook at Razi Berry, on Instagram at Razi.Berry, join her Love is Medicine group to explore the convergence of love and health, and find more Love is Medicine podcast episodes here.

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