Razi Berry

Sugary drinks and artificially sweetened beverages are associated with a higher risk of cardiovascular disease, which suggests artificially sweetened beverages may not be the healthy alternative they are often claimed to be, according to a research letter in the Journal of the American College of Cardiology.

Diets including beverages sweetened with sugar can have a negative impact on cardio-metabolic health

Research has shown that diets including beverages sweetened with sugar can have a negative impact on cardio-metabolic health. Artificially sweetened drinks have been suggested as a healthier alternative, but their impact on cardiovascular health is not fully known. In this paper, researchers looked at data from the French NutriNet-Santé cohort to investigate the relationship between the risk of cardiovascular disease and consuming sugary drinks and artificially sweetened drinks.

Records for 104,760 participants were included

Records for 104,760 participants were included. They were asked to fill out three validated web-based 24-hour dietary records every six months. Artificially sweetened beverages were defined as those containing non-nutritive sweeteners. Sugary drinks consisted of all beverages containing 5% or more sugar. For each beverage category, participants were divided into non-consumers, low consumers and high consumers.

Researchers looked at first incident cases of cardiovascular disease during follow-up from 2009-2019

Researchers looked at first incident cases of cardiovascular disease during follow-up from 2009-2019, which were defined as stroke, transient ischemic attack, myocardial infarction, acute coronary syndrome and angioplasty. After excluding the first three years of follow-up to account for potential reverse causality bias, 1,379 participants had first incident cases of cardiovascular disease. Compared to non-consumers, both higher consumers of sugary drinks and of artificially sweetened beverages had higher risks of first incident cardiovascular disease, after taking into account a wide range of confounding factors.

In addition to a higher risk of heart health issues, Eloi Chazelas, PhD student, lead author of the study and a member of the Nutritional Epidemiology Research Team (Sorbonne Paris Nord University, Inserm, Inrae, Cnam) said the study may have further regulatory implications.

Artificially sweetened beverages may not be a healthy substitute for sugar drinks

“Our study suggests artificially sweetened beverages may not be a healthy substitute for sugar drinks, and these data provide additional arguments to fuel the current debate on taxes, labeling and regulation of sugary drinks and artificially sweetened beverages,” Chazelas said.

Researchers said to establish a causal link between sugary and artificially sweetened beverages and cardiovascular disease, replication in large-scale prospective cohorts and mechanistic investigations will be needed.

1. Eloi Chazelas, Charlotte Debras, Bernard Srour, Léopold K. Fezeu, Chantal Julia, Serge Hercberg, Mélanie Deschasaux, Mathilde Touvier. Sugary Drinks, Artificially-Sweetened Beverages, and Cardiovascular Disease in the NutriNet-Santé Cohort. Journal of the American College of Cardiology, 2020; 76 (18): 2175 DOI: 10.1016/j.jacc.2020.08.075


Razi Berry is the founder and publisher of the journal Naturopathic Doctor News & Review, which has been in print since 2005, and the premier consumer-faced website of naturopathic medicine, NaturalPath. She is the host of The Love is Medicine Project docuseries, The Natural Cancer Prevention Summit, The Heart Revolution-Heal, Empower and Follow Your Heart, and the popular 10-week Sugar Free Summer program. From a near death experience as a young girl that healed her failing heart, to later overcoming infertility and chronic fatigue syndrome and fibromyalgia through naturopathic medicine, Razi has lived the mind/body healing paradigm. Her projects uniquely capture the tradition and philosophy of naturopathy: The healing power of nature, the vital life force in every living thing and the undeniable role that science and mind/body medicine have in creating health and overcoming dis-ease. You can follow Razi on social media: Facebook at Razi Berry, Instagram at Razi.Berry and join the Love is Medicine group to explore the convergence of love and health. Look for more, and listen to more Love is Medicine podcast episodes here.

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