Razi Berry

It’s next to impossible to avoid occasions where the smells and sights of food will tantalize and torment us. Part of the difficulty in resisting these delicious items is a hormone found in the stomach that signals hunger – ghrelin. This hormone is currently being studied as a factor in overeating and obesity.

The Ghrelin Gremlin

A new study on ghrelin was published earlier this month in Cell Reports,that demonstrates that ghrelin encourages eating and the production of dopamine. Dopamine is a neurotransmitter that is commonly thought to support many addictive behaviors through its connection to a positive reward response.

38 individuals was injected with ghrelin

In the study, a group of 38 individuals was injected with ghrelin and then exposed to a range of different smells, both food and non-food. The participants were also shown images of neutral random items intended to be “neutral images,” in order to connect the smells with the images over time.

Brain activity analyzed via fMRI

Functional magnetic resonance imaging (fMRI) was utilized to analyze brain activity in areas where dopamine is known to be involved with the reward response. The results showed that activity in these dopamine responsive areas was higher in those who had been injected with ghrelin, but only when responding to images that had been associated with food smells. It was concluded that ghrelin is controlling the extent to which the brain connects reward to food smells.

Participants also scored the pleasantness of the images associated with food smells. The results of this showed that ghrelin both reduced the response time and increased the perceived pleasantness of food-associated images, but no effect on other images.

Research shows ghrelin may have a larger role in the increased response to food cues

The researchers shows that ghrelin may have a larger role to play in the increased response many have to food cues, and how this response ultimately leads to a struggle with overeating and food addiction.


Razi Berry is the founder and publisher of  the journal Naturopathic Doctor News & Review  that has been in print since 2005 and the premier consumer-faced website of naturopathic medicine, NaturalPath.  She is the host of The Natural Cancer Prevention Summit and The Heart Revolution-Heal, Empower and Follow Your Heart, and the popular 10 week Sugar Free Summer program. From a near death experience as a young girl that healed her failing heart, to later overcoming infertility and Chronic Fatigue Syndrome and Fibromyalgia through naturopathic medicine, Razi has lived the mind/body healing paradigm. Her projects uniquely capture the tradition and philosophy of naturopathy: The healing power of nature, the vital life force in every living thing and the undeniable role that science and mind/body medicine have in creating health and overcoming dis-ease. Follow Razi on Facebook at Razi Berry and join us at  Love is Medicine  to explore the convergence of love and health.

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