This study looked at 51 participants all with IBS, and found that 82 percent were vitamin D deficient. When participants rated their quality of life, there also appeared to be an association between vitamin D levels and the severity of the deficiency. For example, those with lower rated quality of life, based on how IBS affects activities of daily living, showed lower vitamin D levels and a greater deficiency.
Although there is no single known cause that is responsible for IBS, these findings suggest there may be a need to consider supplementation of vitamin D in this population. It is also not been confirmed whether vitamin D deficiency is solely a consequence of the disease, but regardless, insufficient vitamin D status should be addressed in patients with IBS. It is suggested that these patients may also benefit from supplementation, as perceived quality of life may be improved as vitamin D levels normalize.
Simon Tazzyman, Nicholas Richards, Andrew R Trueman, Amy L Evans, Vicky A Grant, Iveta Garaiova, Sue F Plummer, Elizabeth A Williams, Bernard M Corfe. Vitamin D associates with improved quality of life in participants with irritable bowel syndrome: outcomes from a pilot trial. BMJ Open Gastroenterology, 2015; e000052 DOI: 10.1136/bmjgast-2015-000052